Grand Challenges in Bioinformatics and Computational Biology

Grand Challenges in Bioinformatics and Computational Biology

The terms “bioinformatics” and “computational biology” are only about 20 years old – their first appearance in the Medline database may have been as the keywords for the 1990 article describing the first steps of the National Center for Biotechnology Information (Benson et al., 1990). But the mathematical approaches toward the analysis of the structure, function, and evolution of biopolymers ha...

GRAND CHALLENGES Grand challenges in organismal biology

Grand challenges in organismal biology Kurt Schwenk,* Dianna K. Padilla, George S. Bakken and Robert J. Full Department of Ecology and Evolutionary Biology, University of Connecticut, Storrs, CT 06269-3043, USA; Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794-5245, USA; Department of Biology and Center for Biodiversity Studies, Indiana State University, Terre ...

Grand challenges in migration biology.

Billions of animals migrate each year. To successfully reach their destination, migrants must have evolved an appropriate genetic program and suitable developmental, morphological, physiological, biomechanical, behavioral, and life-history traits. Moreover, they must interact successfully with biotic and abiotic factors in their environment. Migration therefore provides an excellent model syste...

Grand challenges in computational physics

Grand challenges in computational physics